Mike Murillo’s Inspiring Battle: From Cancer to the Race Track

For years, Mike Murillo has been a powerhouse in the street racing world, earning respect as a fierce competitor and fan favorite on Street Outlaws. But in recent years, his most intense battle hasn’t been on the track—it’s been for his life. Murillo has faced a brutal health journey that tested his strength, resilience, and determination. Now, with his cancer in remission and his sights set on the future, his story is one of perseverance, hope, and the unbreakable bond between a racer and his fans.

Photo by Mike Murillo Racing 

A Life-Changing Diagnosis

Murillo’s health struggles began in late 2022 when he was diagnosed with Stage 4 non-small cell lung cancer. It was a shocking and devastating blow for someone who had never smoked. Murillo believes that years of tuning cars in poorly ventilated spaces, constantly exposed to exhaust fumes, may have contributed to his illness—a harsh reality for many in the automotive industry.

His diagnosis came after a terrifying battle with COVID-19 in 2021, during which he was hospitalized in critical condition for seven days. He later revealed that he was the only survivor among seven patients on his hospital floor—a testament to his will to fight. But just when he thought he had overcome one major health challenge, cancer threatened to take him down.

Fighting Back with Everything He Had

Murillo’s diagnosis was grim—cancer had spread to his lungs, spine, and lymph nodes. However, doctors found he had a rare genetic mutation that made him eligible for a targeted therapy drug called Rozlytrek. Combined with radiation therapy and Zometa bone infusions, this treatment plan began to turn the tide in his favor.

Photo by Mike Murillo Racing 

By mid-2023, scans showed remarkable progress. The tumor in his lung had turned into scar tissue, his lymph nodes returned to normal, and the mass on his spine had healed. Then, in November 2023, he received the news he had fought so hard for: remission.

The Battle Beyond Cancer

While remission was a victory, the fight didn’t end there. Murillo has faced a grueling recovery, dealing with the side effects of medication, including severe nerve pain, extreme sensitivity to heat and sunlight, and intense skin rashes. On top of that, in early 2023, he underwent double knee replacement surgery—a procedure made even more difficult by his packed racing schedule, which left him little time for proper rehabilitation.

To make matters worse, an accident involving a scooter left his right kneecap broken in half, requiring yet another surgery. But if there’s one thing Murillo doesn’t do, it’s quit.

A New Focus on Health

One of Murillo’s biggest challenges throughout his treatment was weight gain. At his heaviest, he reached 320 pounds due to steroids, poor diet, and a sedentary lifestyle. Determined to take control of his health, he made major changes—cutting out sugar, eliminating late-night snacking, and experimenting with weight loss medications like Mounjaro and semaglutide. His efforts paid off, and by mid-2023, he had dropped 70 pounds. Now, in early 2025, he’s down to the high 250s and remains committed to improving his fitness.

Looking Ahead: Racing, Family, and Giving Back

Although he’s not yet at 100%, Murillo is determined to make the most of his second chance. He plans to address his knee issues during the off-season, ensuring he’s ready to get back behind the wheel for the upcoming racing season. His passion for street racing remains as strong as ever, and he’s eager to prove that he’s still a force to be reckoned with.

Beyond racing, Murillo has become an advocate for health awareness. He encourages others in the automotive industry to take precautions against prolonged exposure to harmful fumes and to prioritize early detection and proactive healthcare. His cancer was initially overlooked due to lung damage from COVID-19, and he hopes his story serves as a wake-up call for others to listen to their bodies and seek medical attention when something feels off.

On a personal level, Murillo has been reflecting on the importance of family. The tragic loss of his father in 2023 has been one of the toughest challenges of his life, but it has also reinforced his commitment to cherishing every moment with loved ones. He plans to create a video raising awareness about home safety and the value of treasuring time with family.

The Unbreakable Bond with His Fans

Through it all, Murillo has never been alone. His fans—his extended family—have been a source of strength, support, and encouragement. Their prayers, messages, and unwavering belief in him have helped him push through even the darkest moments. He’s committed to being transparent about his journey, sharing both the highs and lows to inspire others facing similar battles.

A Legacy of Strength and Determination

Mike Murillo’s story isn’t just about beating cancer—it’s about overcoming adversity, finding purpose in the struggle, and emerging stronger than ever. His resilience, positive outlook, and relentless determination continue to inspire not just the racing community but anyone facing tough battles of their own.

As he prepares for his next round of scans in February 2025, Murillo remains both hopeful and realistic. Cancer is unpredictable, but he refuses to let it define him. His message is clear: “I’m alive, and I’m grateful. Let’s make 2025 the best it can possibly be.”

No matter what the road ahead holds, one thing is certain—Mike Murillo isn’t done fighting, racing, or inspiring those who follow his journey. His spirit, his passion, and his love for the sport will keep him pushing forward, proving that true champions never back down.